Investigational New Drugs

Chemo-immunotherapy of colorectal carcinoma: preclinical rationale and clinical experience
pp. 99-110(12)
Authors: Correale, Pierpaolo; Cusi, Maria; Micheli, Lucia; Nencini, Cristina; Vecchio, Maria; Torino, Francesco; Aquino, Angelo; Bonmassar, Enzo; Francini, Guido; Giorgi, Giorgio

Novel in vitro model barriers for evaluation of the permeability of antitumor compounds, thioxanthones
pp. 111-116(6)
Authors: Marasanapalle, Venugopal; Li, Xiaoling; Polin, Lisa; Jasti, Bhaskara

Phase I study of gefitinib, oxaliplatin, 5-fluorouracil, and leucovorin (IFOX) in patients with advanced solid malignancies
pp. 117-123(7)
Authors: Cho, Cheryl; Fisher, George; Halsey, Joanne; Sikic, Branimir

A phase I safety and dose escalation trial of docetaxel combined with GEM®231, a second generation antisense oligonucleotide targeting protein kinase A R1α in patients with advanced solid cancers
pp. 125-134(10)
Authors: Goel, Sanjay; Desai, Kavita; Macapinlac, Manuel; Wadler, Scott; Goldberg, Gary; Fields, Abbie; Einstein, Mark; Volterra, Fabio; Wong, Benny; Martin, Russell; Mani, Sridhar

Phase II, parallel-design study of preoperative combined modality therapy and the matrix metalloprotease (mmp) inhibitor prinomastat in patients with esophageal adenocarcinoma
pp. 135-140(6)
Authors: Heath, Elisabeth; Burtness, Barbara; Kleinberg, Lawrence; Salem, Ronald; Yang, Stephen; Heitmiller, Richard; Canto, Marcia; Knisely, Jonathan; Topazian, Mark; Montgomery, Elizabeth; Tsottles, Nancy; Pithavala, Yazdi; Rohmiller, Bridget; Collier, Mary; Forastiere, Arlene

A randomized phase II trial of interleukin-2 in combination with four different doses of bryostatin-1 in patients with renal cell carcinoma
pp. 141-149(9)
Authors: Peterson, Amy; Harlin, Helena; Karrison, Theodore; Vogelzang, Nicholas; Knost, James; Kugler, John; Lester, Eric; Vokes, Everett; Gajewski, Thomas; Stadler, Walter

Multicenter phase II study of amrubicin, 9-amino-anthracycline, in patients with advanced non-small-cell lung cancer (Study 1): West Japan Thoracic Oncology Group (WJTOG) trial
pp. 151-158(8)
Authors: Sawa, Toshiyuki; Yana, Takashi; Takada, Minoru; Sugiura, Takahiko; Kudoh, Shinzoh; Kamei, Tadashi; Isobe, Takeshi; Yamamoto, Hidehiko; Yokota, Soichiro; Katakami, Nobuyuki; Tohda, Yuji; Kawakami, Akira; Nakanishi, Yoichi; Ariyoshi, Yutaka

Phase II trial of DNA methyltransferase 1 inhibition with the antisense oligonucleotide MG98 in patients with metastatic renal carcinoma: A National Cancer Institute of Canada Clinical Trials Group investigational new drug study
pp. 159-167(9)
Authors: Winquist, Eric; Knox, Jennifer; Ayoub, Jean-Pierre; Wood, Lori; Wainman, Nancy; Reid, Gregory; Pearce, Laura; Shah, Ajit; Eisenhauer, Elizabeth