Adaptation dynamics in pattern-reversal visual evoked potentials

Authors: Heinrich S.P.; Bach M.

Source: Documenta Ophthalmologica, Volume 102, Number 2, March 2001 , pp. 141-156(16)

Publisher: Springer

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Abstract:

Recording a VEP usually involves prolonged repetitions of the stimulus, but the influence of adaptation is rarely discussed in this context. Two experiments were performed. In Experiment 1 the time course of the response amplitude during steady-state stimulation was assessed. During the first seconds of stimulation we found an increase in amplitude, followed by a continuous exponential decline. This confirmed earlier results. There is considerable inter-subject variability concerning all aspects of the time course in our 19 subjects. Experiment 2 used two types of transient pattern reversal stimuli: one regular stimulus as used in standard clinical applications and one with a pause in between each reversal. N1 and P1 amplitudes did not show significant differential effects. N2 amplitude was reduced by 73% in the standard condition whereas P1 peak time increased slightly but significantly (3.2 ms).

Keywords: evoked potentials; VEP; adaptation; steady-state; transient; pattern reversal

Language: English

Document Type: Regular paper

Affiliations: 1: Elektrophysiologisches Labor, Univ.-Augenklinik Freiburg, Killianstr. 5, 79106 Freiburg, Germany

Publication date: 2001-03-01