A New Noninvasive Device for Measuring Central Ejection dP/dt

Authors: Miguel Gorenberg¹; Alon Marmor²; Hector Rotstein³

Source: Cardiovascular Engineering: An International Journal, Volume 4, Number 4, December 2004 , pp. 305-310(6)

Publisher: Springer

Abstract:

The current study describes a new noninvasive device for measuring central ejection dP/dt (dP/dt_ejc). The device consists of a sphygmonometric arm cuff and an array of proprietary sensors attached to the arm at the antecubital space over the brachial artery, and a computerized monitoring system. Noninvasive systolic pressure wave forms are generated by measuring time delay between the first sensor on the array serving as a reference and onset of brachial artery flow in subsequent sensors during controlled upper arm deflation. The delay decreases with falling cuff pressure so that the plot of pressure versus time delays yields ascending portion of arterial wave form. The present study describes our initial experience in 16 patients with coronary artery disease undergoing percutaneous transluminal coronary angioplasty. Noninvasive measurements were performed at baseline, after balloon inflation and at the end of catheterization. Mean balloon occlusion time was 37 ± 10 s. In 14 of 16 patients, dP/dt_ejc decreased from 149 ± 29 to 120 ± 33 (p < 0.0002). In 11 of 14, an immediate return to near baseline values after deflation (136±28 p < 0.001) occurred.

Keywords: noninvasive; ischemia; percutaneous transluminal coronary angioplasty; aortic dP/dt

Document Type: Research article

DOI: http://dx.doi.org/10.1007/s00270-005-8756-5

Affiliations: 1: Department of Nuclear Cardiology and Nuclear Medicine, Sieff Government Hospital, Safed, Israel, Email: miggoren@actcom.co.il 2: Department of Cardiology, Sieff Government Hospital, Safed, Faculty of Medicine, Technion Institute of Technology, Haifa, Israel, 3: Department of Electrical Engineering, Technion Institute of Technology, Haifa, Israel,

Publication date: 2004-12-01

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