The Economic Efficiency of Amlodipine in the Treatment of Coronary Atherosclerosis—An Analysis Based on the PREVENT Study
Authors: Cathomas G.1; Erne P.2; Schwenkglenks M.1; Szucs T.D.3
Source: Cardiovascular Drugs and Therapy, Volume 16, Number 1, January 2002 , pp. 61-66(6)
Publisher: Springer
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Abstract:
Background: High health service expenditure on the one hand, and the politically declared objective of stability of statutory contributions and restriction of public funds on the other hand, have been central points of the political and social discussion for several years. The over-proportional increase in health service expenditure is obvious, compared to the increase in the costs of living.
Patients and Methods: Cost-effectiveness of amlodipine in the treatment of coronary atherosclerosis was analysed by applying the results of the PREVENT study to the Swiss health system.
Results: Calculation of effectiveness shows an additional life expectancy of 0.083 years in the amlodipine cohort compared to the placebo cohort, over an observation period of 3 years. The cost-effectiveness of amlodipine treatment is approximately CHF 14,650 per life-year gained.
Conclusion: The administration of the calcium antagonist amlodipine in CHD patients is cost-effective.
Keywords: medical economics; coronary artery disease; cost effectiveness; calcium antagonists
Language: English
Document Type: Regular paper
Affiliations: 1: Medical Department, Hirslanden Research, Zurich, Switzerland 2: Department of Cardiology, Kantonsspital Lucerne, Switzerland 3: Department of Cardiology, Kantonsspital Lucerne, Switzerland. thomas.szucs@hirslanden.ch
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