Method of Experimental Constriction of Renal Artery for Modeling of Renovascular Hypertension in Rats

Authors: S. N. Kharin; V. V. Krandycheva

Source: Bulletin of Experimental Biology and Medicine, Volume 138, Number 1, July 2004 , pp. 103-105(3)

Publisher: Springer

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Abstract:

We propose a method of constriction of the renal artery consisting in pulling of a loop of isolated artery into a thin plastic tube with calibrated inner diameter. This method can be used in experiments with constriction of other small blood vessels to diminish the local blood flow.

Keywords: renal artery; renovascular hypertension; arterial pressure; myocardial hypertrophy; rat

Document Type: Research article

DOI: http://dx.doi.org/10.1023/B:BEBM.0000046952.32677.e8

Affiliations: 1: Laboratory of Cardiodynamics, Institute of Physiology, Komi Research Center, Ural Division of the Russian Academy of Sciences, Syktyvkar., Email: s.kharin@physiol.komisc.ru

Publication date: 2004-07-01