Prooxidant Effects of Nitrofurantoin

Authors: Novikov O.O.¹; Pokrovskii M.V.¹; Konovalenko A.B.¹

Source: Bulletin of Experimental Biology and Medicine, Volume 134, Number 2, August 2002 , pp. 148-150(3)

Publisher: Springer

Abstract:

We studied the possibility of using prooxidant effects of nitrofurantoin (furadonin) for stimulation of the natural antioxidant systems for preventing myocardial damage after coronary occlusion. A pronounced cardioprotective effect of the drug was observed.

Keywords: 5-nitrofuranes; nitrofurantoin; toxicity; lipid peroxidation; cardioprotective effect

Language: English

Document Type: Research article

Affiliations: 1: Kursk State Medical University

Links for this article

http://www.ingentaconnect.com/klu/bebm/2002/00000134/00000002/00457428
http://openurl.ingenta.com/content?genre=article&issn=0007-4888&volume=134&issue=2&spage=148&epage=150