Prooxidant Effects of Nitrofurantoin

Authors: Novikov O.O.1; Pokrovskii M.V.1; Konovalenko A.B.1

Source: Bulletin of Experimental Biology and Medicine, Volume 134, Number 2, August 2002 , pp. 148-150(3)

Publisher: Springer

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Abstract:

We studied the possibility of using prooxidant effects of nitrofurantoin (furadonin) for stimulation of the natural antioxidant systems for preventing myocardial damage after coronary occlusion. A pronounced cardioprotective effect of the drug was observed.

Keywords: 5-nitrofuranes; nitrofurantoin; toxicity; lipid peroxidation; cardioprotective effect

Language: English

Document Type: Research article

Affiliations: 1: Kursk State Medical University

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