Pleomorphic xanthoastrocytoma of the cerebellum: illustrated review

Authors: Gil-Gouveia, R.¹; Cristino, N.²; Farias, J. P.²; Trindade, A.²; Ruivo, N. S.³; Pimentel, J.¹

Source: Acta Neurochirurgica, Volume 146, Number 11, November 2004 , pp. 1241-1244(4)

Publisher: Springer

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Abstract:

Although rarely, the usually benign, supratentorial, grade II astrocytic tumour pleomorphic xanthoastrocytoma (PXA) may arise from the cerebellum. A review of the published cases of these PXAs is made including the author's own case of a 40 years-old man with a right cerebellopontine angle tumour, which recurred after a gross total resection.

The major clinical and histopathological features of cerebellar PXAs are discussed, and factors playing a role in their biological behaviour, like post-surgical medical treatment, genetics and extent of leptomeningeal seeding are stressed.

Keywords: Cerebellum; glioma; pleomorphic xanthoastrocytoma

Document Type: Research article

DOI: http://dx.doi.org/10.1007/s00701-004-0366-5

Affiliations: 1: Laboratory of Neuropathology, Institute of Molecular Medicine, Hospital de Santa Maria, Lisboa, Portugal, 2: Neurosurgery Department, 011011011011011011Hospital de Santa Maria, Lisboa, Portugal, 3: Neuroradiology Department, Hospital de Santa Maria, Lisboa, Portugal,

Publication date: 2004-11-01