IngentaConnect Five highly informative X-chromosomal STRs in Koreans

Authors: Shin, Kyoung-Jin¹; Kwon, Byung-Ki²; Lee, Sang-Seob³; Yoo, Ji-Eun⁴; Park, Myung⁴; Chung, Ukhee⁴; Lee, Hwan⁴; Han, Gil-Ro²; Choi, Jong-Hoon⁴; Kim, Chong-Youl⁴

Source: International Journal of Legal Medicine, Volume 118, Number 1, February 2004 , pp. 37-40(4)

Publisher: Springer

Abstract:

The five X-chromosomal short tandem repeats (STRs) GATA172D05, HPRTB, DXS8377, DXS101 and HumARA were analyzed in 150 males and 150 females from Korea. Markers were amplified in a quadruplex and a monoplex PCR reaction with fluorescently labeled primers. For accurate and reproducible STR typing, sequenced allelic ladders were constructed and a Genotyper macro was programmed. Some differences were found on comparing the allele frequencies of Koreans with those of other populations in DXS8377, DXS101 and HumARA. The forensic efficiency parameters showed that the five X-linked STRs are highly informative for forensic application in Koreans.

Keywords: STR; X-chromosome; Korea

Document Type: Research article

DOI: 10.1007/s00414-003-0415-2

Affiliations: 1: Department of Forensic Medicine, College of Medicine, Yonsei University, 134 Shinchon-Dong, Seodaemun-Gu, 120-752, Seoul, Korea , Email: kjshin@yumc.yonsei.ac.kr 2: Biometrics Engineering Research Center, Yonsei University, 134 Shinchon-Dong, Seodaemun-Gu, 120-749, Seoul, Korea, 3: Human Identification Research Institute, Yonsei University, 134 Shinchon-Dong, Seodaemun-Gu, 120-752, Seoul, Korea , 4: Department of Forensic Medicine, College of Medicine, Yonsei University, 134 Shinchon-Dong, Seodaemun-Gu, 120-752, Seoul, Korea ,

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