@article {Aktan:January 2004:0932-0067:134, author = "Aktan, Erdal", author = "Bozkurt, Kaan", author = "Ozer, Dilek", author = "Yucebilgin, Sait", author = "Karadadas, Nedim", author = "Bilgin, Onur", title = "The effect of mid-luteal estradiol level on the outcome of ICSI-ET cycles", journal = "Archives of Gynecology and Obstetrics", volume = "269", year = "January 2004", abstract = "We investigated if mid-luteal estradiol levels could predict the outcome in intracytoplasmic sperm injection embryo transfer (ICSI-ET) cycles (n=231). Pregnant and non-pregnant women were compared regarding their peak estradiol levels on human chorionic gonadotropin (hCG) injection day, and mid-luteal estradiol levels on the 7th day following oocyte recovery. Pregnancy rates of the groups that were designed according to the "peak/mid-luteal estradiol level" and the mid-luteal estradiol levels were also compared.

Peak and mid-luteal estradiol levels in pregnant women were higher than in non-pregnant women in all patients, although the difference between peak and mid-luteal estradiol levels were similar in pregnant and non-pregnants. Pregnant women had higher mid-luteal estradiol levels in good responders, but the peak estradiol levels of pregnant and non-pregnant women were similar. In poor responders, pregnant and non-pregnant women were similar with respect to peak and mid-luteal estradiol levels. Both in all patients and good responders, women with mid-luteal estradiol levels <200 pg/ml had lower pregnancy rates than those with >2,000 pg/ml. Peak/mid-luteal estradiol ratios of pregnant and non-pregnant women were not significantly different in all patients, good responders and poor responders; although a tendency for a lower ratio in pregnants was encountered in good responders. Pregnancy rates of the groups according to the "peak/mid-luteal estradiol ratio" were similar; in all patients, good responders and poor responders.

A relation between the mid-luteal estradiol level and the outcome is encountered only in good responders.", pages = "134-138(5)", url = "http://www.ingentaconnect.com/content/klu/404/2004/00000269/00000002/art00013" doi = "doi:10.1007/s00404-003-0533-6" }