@article {Tontisirin:October 2007:0256-7040:1163,
	author = "Tontisirin, Nuj",
	author = "Armstead, William",
	author = "Waitayawinyu, Pichaya",
	author = "Moore, Anne",
	author = "Udomphorn, Yuthana",
	author = "Zimmerman, Jerry",
	author = "Chesnut, Randall",
	author = "Vavilala, Monica",
	title = "Change in cerebral autoregulation as a function of time in children after severe traumatic brain injury: a case series",
	journal = "Child's Nervous System",
	volume = "23",
	year = "October 2007",
	abstract = "The objective of this study was to describe changes in cerebral autoregulation after severe pediatric traumatic brain injury (TBI).<P></P>Two cerebral autoregulation tests were performed during the first 10 days after severe TBI in children &#60;16 years. Cerebral autoregulation was quantified using the mean autoregulatory index (mARI).<P></P>Nine (five males/four females) children (10&#8201;&#177;&#8201;5 years) with severe (admission Glasgow Coma Scale (GCS), 5&#8201;&#177;&#8201;2) TBI were enrolled. Thirty (3/9) percent of initial exams revealed impaired cerebral autoregulation; all three had returned to intact cerebral autoregulation on second exam. However, in three of nine (33%) patients, cerebral autoregulation worsened on second exam. Of the factors examined, worsening mARI on second exam was associated with worsening head computed tomography (CT) lesion.<P></P>Cerebral autoregulation often changed and worsened during the first 9 days after severe pediatric TBI. Worsening cerebral autoregulation may mirror worsening TBI.",
	pages = "1163-1169(7)",
	url = "http://www.ingentaconnect.com/content/klu/381/2007/00000023/00000010/00000339"
	doi = "doi:10.1007/s00381-007-0339-0"
}