Chronic thromboembolic pulmonary hypertension — assessment by magnetic resonance imaging

Authors: Kreitner, Karl-Friedrich; Kunz, R.; Ley, Sebastian; Oberholzer, Katja; Neeb, Daniel; Gast, Klaus; Heussel, Claus-Peter; Eberle, Balthasar; Mayer, Eckhard; Kauczor, Hans-Ulrich; Düber, Christoph

Source: European Radiology, Volume 17, Number 1, January 2007 , pp. 11-21(11)

Publisher: Springer

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Abstract:

Chronic thromboembolic pulmonary hypertension (CTEPH) is a severe disease that has been ignored for a long time. However, with the development of improved therapeutic modalities, cardiologists and thoracic surgeons have shown increasing interest in the diagnostic work-up of this entity. The diagnosis and management of chronic thromboembolic pulmonary hypertension require a multidisciplinary approach involving the specialties of pulmonary medicine, cardiology, radiology, anesthesiology and thoracic surgery. With this approach, pulmonary endarterectomy (PEA) can be performed with an acceptable mortality rate. This review article describes the developments in magnetic resonance (MR) imaging techniques for the diagnosis of chronic thromboembolic pulmonary hypertension. Techniques include contrast-enhanced MR angiography (ce-MRA), MR perfusion imaging, phase-contrast imaging of the great vessels, cine imaging of the heart and combined perfusion-ventilation MR imaging with hyperpolarized noble gases. It is anticipated that MR imaging will play a central role in the initial diagnosis and follow-up of patients with CTEPH.

Keywords: Magnetic resonance imaging techniques; Chronic thromboembolic pulmonary hypertension

Document Type: Research article

DOI: http://dx.doi.org/10.1007/s00330-006-0327-x

Affiliations: 1: Email: kreitner@radiologie.klinik.uni-mainz.de

Publication date: 2007-01-01