Hypertrophic pulmonary osteoarthropathy (HPOA) (Pierre Marie-Bamberger syndrome): two cases presenting as acute inflammatory arthritis. Description and review of the literature

Authors: Armstrong, David; McCausland, Elisabeth; Wright, Gary

Source: Rheumatology International, Volume 27, Number 4, February 2007 , pp. 399-402(4)

Publisher: Springer

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Abstract:

We report the cases of two middle-aged male smokers who presented to the early synovitis clinic with an acute phase response, synovitis of the wrists and ankles and clubbing of the fingers, but no respiratory symptoms. Both proved to have primary lung tumours with hypertrophic pulmonary osteoarthropathy, in one case resolving promptly with treatment of the carcinoma. We review the literature, including theories on pathogenesis.

Keywords: HPOA; Hypertrophic pulmonary osteoarthropathy; Paraneoplasic; Finger clubbing; Rheumatoid arthritis

Document Type: Research article

DOI: http://dx.doi.org/10.1007/s00296-006-0224-2

Affiliations: 1: Email: oswald17727@hotmail.com

Publication date: 2007-02-01