Relationship between cerebroplacental Doppler ratio and birth weight in postdates pregnancies

Authors: H. Lam; W. C. Leung; C. P. Lee; T. T. Lao

Source: Ultrasound in Obstetrics and Gynecology, Volume 25, Number 3, March 2005 , pp. 265-269(5)

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Abstract:

Objectives

To explore the relationship between cerebroplacental Doppler impedance index and birth weight in postdates pregnancies, and to evaluate the use of a combination of Doppler parameters and ultrasound biometry in the prediction of large-for-gestational age (LGA) fetuses at 41 weeks of gestation.

Methods

The pulsatility indices of the umbilical (UA-PI) and middle cerebral (MCA-PI) arteries, the cerebroplacental pulsatility index ratio (CPR) and the estimated fetal weight (EFW) were obtained in a cohort of 181 ultrasound-dated pregnancies at 41 weeks' gestation, 2 days before induction of delivery. A regression equation was established and the correlation between umbilical artery impedance and different birth-weight centile groups was determined. A receiver–operating characteristics (ROC) curve was used to compare prediction of LGA fetuses using biometry alone with that using biometry and UA-PI.

Results

UA-PI was inversely related to EFW (Spearson's correlation coefficient rho = -0.28, P < 0.001). Logistic regression showed an independent contribution of UA-PI to the birth-weight estimation (birth weight = 1356.8 - 232.0 × UA-PI + 0.65 × EFW). On ROC curve analysis, the prediction of LGA with the regression equation was comparable to that using ultrasound biometry alone.

Conclusion

UA-PI was inversely correlated to EFW, but the combination of ultrasound biometry and UA-PI compared with biometry alone showed similar prediction of LGA fetuses in postdates pregnancies. Further prospective trials on larger populations or groups with a higher prevalence of LGA fetuses would be needed to validate the use of the new formula. Copyright © 2005 ISUOG. Published by John Wiley & Sons, Ltd.

Keywords: cerebroplacental Doppler; large for gestation; postdates

Document Type: Research article

DOI: http://dx.doi.org/10.1002/uog.1794

Affiliations: 1: Department of Obstetrics and Gynaecology, University of Hong Kong, HKSAR, China

Publication date: 2005-03-01

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Relationship between cerebroplacental Doppler ratio and birth weight in postdates pregnancies

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