Skip to main content

Acute changes of cerebral venous blood flow in growth‐restricted human fetuses in response to uterine contractions

The full text article is not available for purchase.

The publisher only permits individual articles to be downloaded by subscribers.

Abstract:

Objective

The fetal cerebral venous circulation during acute hypoxic stress provoked by uterine contractions has not been studied previously. The aim of this study was to explore the cerebral venous circulation during an oxytocin challenge test (OCT) in intrauterine growth‐restricted (IUGR) fetuses.

Methods

Doppler recordings of blood flow in the vein of Galen (GV), straight sinus (SS) and transverse sinus (TS) before and during uterine contractions and relaxation were obtained at the same time as electronic fetal heart rate (FHR) monitoring in 44 term IUGR fetuses. The OCT was classified as negative (normal FHR) or positive (late FHR decelerations). Non‐parametric statistics were used to test differences between OCT groups.

Results

In OCT‐negative cases (n = 39), de novo pulsations occurred in the GV, and SS flow velocities increased during contractions compared with basal measurements. There were no significant differences in TS flow. Flow recordings were less often obtained from OCT‐positive cases (n = 5), making comparisons with OCT‐negative cases uncertain.

Conclusions

In uncompromised IUGR fetuses an acute cerebral venous hyperperfusion develops in response to uterine contractions. Pulsations in the GV are detected but are unlikely to be an ominous sign in this situation. The more centrally located TS was less discriminating for acute cerebral venous blood flow changes. Copyright © 2004 ISUOG. Published by John Wiley & Sons, Ltd.

Keywords: Doppler; contraction; flow; labor; oxytocin; pregnancy; resistance; uterine; venous

Document Type: Research Article

DOI: https://doi.org/10.1002/uog.1709

Affiliations: Department of Obstetrics and Gynecology, Malmö University Hospital, Lund University, Malmö, Sweden

Publication date: 2004-10-01

More about this publication?
  • Access Key
  • Free content
  • Partial Free content
  • New content
  • Open access content
  • Partial Open access content
  • Subscribed content
  • Partial Subscribed content
  • Free trial content
Cookie Policy
X
Cookie Policy
Ingenta Connect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more