Skip to main content

Effect of diphacinone on blood coagulation in Spermophilus beecheyi as a basis for determining optimal timing of field bait applications

The full text article is not available for purchase.

The publisher only permits individual articles to be downloaded by subscribers.

Abstract:

The effect was determined of a single dose of 2 mg kg-1 diphacinone on three blood-clotting parameters [Prothrombin Time (PT), Partial Thromboplastin Time (PTT), and Protein Induced by Vitamin K Absence or Antagonists (PIVKA)] over a 120-h period in California ground squirrels, Spermophilus beecheyi. Diphacinone resulted in elevated PT, PTT and PIVKA within 24 h of squirrels receiving the dose. The most significant change was observed 72 h after dosing. As time following diphacinone dosing increased, there was higher individual variation in blood-clotting time. We suggest that increasing the interval between field bait applications should still result in squirrel mortality but reduce the potential for secondary hazards that may occur when squirrels have the opportunity to consume more than one lethal dose of diphacinone.

© 2002 Society of Chemical Industry

Keywords: California ground squirrel; Spermophilus beecheyi; anticoagulant; bait; blood coagulation; diphacinone

Document Type: Research Article

DOI: https://doi.org/10.1002/ps.516

Affiliations: Department of Wildlife, Fish and Conservation Biology, University of California, One Shields Ave, Davis, California, USA

Publication date: 2002-07-01

More about this publication?
  • Access Key
  • Free content
  • Partial Free content
  • New content
  • Open access content
  • Partial Open access content
  • Subscribed content
  • Partial Subscribed content
  • Free trial content
Cookie Policy
X
Cookie Policy
Ingenta Connect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more