Molecular markers of metastasis in squamous carcinomas

Author: Helliwell T.R.^{1, *}

Source: The Journal of Pathology, Volume 194, Number 3, July 2001 , pp. 289-293(5)

Publisher: John Wiley & Sons, Ltd.

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Abstract:

The prognosis for patients with squamous carcinomas of the head and neck region is strongly influenced by the presence or absence of cervical lymph node metastases. Biological markers that indicated a high risk of metastasis would have a major role in determining the optimal therapeutic strategy for these patients. This editorial discusses recent studies of molecular and genetic markers of squamous carcinomas in relation to metastatic potential and highlights some of theissues that limit current progress in this field of study. Copyright © 2001 John Wiley & Sons, Ltd.

Keywords: squamous carcinoma; head and neck neoplasms; lymph node; metastasis; molecular markers

Language: English

Document Type: Editorial

DOI: 10.1002/1096-9896(200107)194:3<289::AID-PATH912>3.0.CO;2-L

Affiliations: 1: Department of Pathology, University of Liverpool, Liverpool, UK *

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