Improvement of Chronic Rhinitis Under Aspirin

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Abstract:

In a subset of aspirin-tolerant asthmatics, administration of aspirin improves respiratory symptoms. We present a patient with chronic rhinosinusitis with nasal polyps who exhibited relief of nasal obstruction and nasal discharge and improvement in the sense of smell following oral administration of 150 mg of aspirin daily. Improvement in the patency of the nasal passages was documented by nasal endoscopy and magnetic resonance imaging. Improvement of olfactory function was documented by validated psychophysical olfactory testing and by means of olfactory event-related potentials.

Keywords: aspirin; nasal polyps; olfaction disorders; salicylic acid; sinusitis

Document Type: Research Article

DOI: http://dx.doi.org/10.4187/respcare.01190

Publication date: March 1, 2012

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