Preliminary Evaluation of a New Index to Predict the Outcome of a Spontaneous Breathing Trial

The full text article is not available for purchase.

The publisher only permits individual articles to be downloaded by subscribers.


BACKGROUND: The available predictors of spontaneous-breathing-trial (SBT) success/failure lack accuracy. We devised a new index, the CORE index (compliance, oxygenation, respiration, and effort). OBJECTIVE: To compare the CORE index to the CROP index (compliance, rate, oxygenation, and pressure), airway-occlusion pressure 0.1 s after the start of inspiratory flow (P0.1), and rapid shallow breathing index (RSBI) for predicting SBT success/failure in a critical care environment. METHODS: With 47 mechanically ventilated patients recovering from respiratory failure, of various causes, we prospectively examined the SBT success/failure prediction accuracy and calculated receiver operating characteristic curves, sensitivity, specificity, and likelihood ratios of CORE, CROP, P0.1, and RSBI. RESULTS: The specificities were CORE 0.95, P0.1 0.70, CROP 0.70, and RSBI 0.65. The sensitivities were CORE 1.00, CROP 1.00, P0.1 0.93, and RSBI 0.89. The areas under the receiver operating characteristic curve were CORE 1.00 (95% CI 0.92‐1.00), CROP 0.91 (95% CI 0.79‐0.97), P0.1 0.81 (95% CI 0.67‐0.91), and RSBI 0.77 (95% CI 0.62‐0.88). The positive likelihood ratios were CORE 20.0, CROP 3.3, P0.1 3.1, and RSBI 2.5. The negative likelihood ratios were CORE 0.0, CROP 0.0, P0.1 0.1, and RSBI 0.2. CONCLUSIONS: The CORE index was the most accurate predictor of SBT success/failure.

Keywords: CROP index; P0.1; mechanical ventilation; rapid shallow breathing index; spontaneous breathing trial

Document Type: Research Article


Affiliations: Respiratory Therapy Department, Hôpital du Sacré-Coeur, Montréal, Québec, Canada.

Publication date: October 1, 2011

More about this publication?
Related content



Share Content

Access Key

Free Content
Free content
New Content
New content
Open Access Content
Open access content
Subscribed Content
Subscribed content
Free Trial Content
Free trial content
Cookie Policy
Cookie Policy
ingentaconnect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more