The Effects of Flow on Airway Pressure During Nasal High-Flow Oxygen Therapy

Authors: Parke, Rachael L; Eccleston, Michelle L; McGuinness, Shay P

Source: Respiratory Care, Volume 56, Number 8, August 2011 , pp. 1151-1155(5)

Publisher: The Journal Respiratory Care Company

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Abstract:

BACKGROUND: Nasal high-flow oxygen therapy increases the mean nasopharyngeal airway pressure in adults, but the relationship between flow and pressure is not well defined. OBJECTIVE: To determine the relationship between flow and pressure with the Optiflow nasal high-flow oxygen therapy system. METHODS: We invited patients scheduled for elective cardiac surgery to participate. Measurements were performed with nasal high-flow oxygen at flows of 30, 40, and 50 L/min, with the patient's mouth both open and closed. Pressures were recorded over one minute of breathing, and average flows were calculated via simple averaging. RESULTS: With the mouth closed, the mean ± SD airway pressures at 30, 40, and 50 L/min were 1.93 ± 1.25 cm H2O, 2.58 ± 1.54 cm H2O, and 3.31 ± 1.05 cm H2O, respectively. There was a positive linear relationship between flow and pressure. CONCLUSIONS: The mean nasopharyngeal pressure during nasal high-flow oxygen increases as flow increases. Australian Clinical Trials Registry http://www.adhb.govt.nz/achicu/hot_2_airway_pressure.htm

Keywords: airway pressure; nasal high-flow therapy; oxygen therapy

Document Type: Research Article

DOI: http://dx.doi.org/10.4187/respcare.01106

Affiliations: Cardiothoracic and Vascular ICU, Auckland City Hospital, Auckland, New Zealand

Publication date: August 1, 2011

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