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Safety and Efficacy of β Agonists

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Abstract:

Both short-acting and long-acting β agonists have been used for many years for the treatment of asthma. Short-acting β agonists are life-saving and their role as rescue agents is unquestioned, but regular use is not recommended because of safety concerns and the effectiveness of asthma-controller medications. Long-acting β agonists are effective controller medications but have safety issues, so their use should be restricted to patients who are not optimally controlled on first-line controllers such as inhaled corticosteroids. The effect of the β receptor genotype on β agonist response is unclear but could hold promise for proper patient management.

Keywords: ASTHMA; BETA AGONISTS; BETA RECEPTOR; GENOTYPE; INHALED CORTICOSTEROIDS

Document Type: Research Article

Affiliations: Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of North Carolina, Chapel Hill, North Carolina

Publication date: May 1, 2008

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