Respiratory Effects of Amyotrophic Lateral Sclerosis: Problems and Solutions

Author: Lechtzin, Noah MD

Source: Respiratory Care, Volume 51, Number 8, August 2006 , pp. 871-884(14)

Publisher: The Journal Respiratory Care Company

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Abstract:

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease. Most patients die from respiratory complications. Fortunately, there are a growing number of treatment options that can improve both survival and quality of life for patients with ALS. This review discusses the respiratory evaluation and treatment of patients with ALS, about which a great deal is known. It also includes material on related problems, such as speech and swallowing difficulties and end-of-life care.

Keywords: AMYOTROPHIC; DIAPHRAGM; LATERAL SCLEROSIS; PULMONARY FUNCTION; RESPIRATORY MUSCLES; VENTILATION

Document Type: Research Article

Affiliations: School of Medicine, Johns Hopkins University, Baltimore, Maryland, Division of Pulmonary and Critical Care Medicine, Department of Medicine, 1830 E Monument Street, Baltimore MD 21205;, Email: nlechtz1@jhmi.edu

Publication date: August 1, 2006

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