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A Novel Device for Measuring Long-Term Oxygen Therapy Adherence: A Preliminary Validation

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INTRODUCTION: Current methods for measuring patient adherence to long-term oxygen therapy fail to measure the actual amount of time the patient is inhaling oxygen and the pattern of oxygen use within the day. We have developed a novel oxygen-adherence monitor to address these limitations, and this report introduces the monitor and provides preliminary data validating its use. METHODS: This battery-powered monitor attaches to the oxygen source and detects respiratoryrelated pressure fluctuations transmitted through the nasal cannula. The monitor takes a measurement over a 25-second period, at 4-min intervals. It detects and stores data on 4 different states that describe the patient's actual use of the oxygen source and nasal cannula: source-off/cannula-off, source-off/cannula-on, source-on/cannula-off, and source-on/cannula-on. We studied the monitor's performance with 10 patients with chronic obstructive pulmonary disease, during a directly-observed sequence of using and not using supplemental oxygen via nasal cannula, while sitting and walking. RESULTS: The monitor correctly detected 122 out of 129 measurements among all participants, yielding a 95% detection accuracy. CONCLUSION: A monitor that objectively measures oxygen inhalation, rather than oxygen expenditure, may help improve the management of patients on long-term oxygen therapy.


Document Type: Research Article

Affiliations: 1: Department of Bioengineering, University of Pennsylvania, 120 Hayden Hall, 3320 Smith Walk, Philadelphia PA 19104;, Email: sunkai.lin@gmail.com 2: Pulmonary, Allergy, and Critical Care Division, Department of Medicine, and with the Center for Sleep and Respiratory Neurobiology, University of Pennsylvania, Philadelphia, Pennsylvania, and with the Philadelphia Veterans Affairs Medical Center, Philadelphia, Pennsylvania 3: Department of Bioengineering, University of Pennsylvania, Philadelphia, Pennsylvania

Publication date: January 1, 2006

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