The Spectrum of Respiratory Care Research: Prospective Clinical Research

Authors: Schwenzer, Karen J.¹; Durbin Jr, Charles G.²

Source: Respiratory Care, Volume 49, Number 10, October 2004 , pp. 1165-1170(6)

Publisher: The Journal Respiratory Care Company

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Abstract:

Prospective clinical research is given the greatest weight in evidence-based clinical practice recommendations, and therefore has the greatest potential to change care and help the largest number of patients. This article briefly describes the history of government regulation of prospective clinical research, how a prospective clinical research project is developed, and how the researcher seeks project approval from the institutional review board. We also evaluate 2 published studies with regard to ethical and regulatory matters that influenced the studies.

Keywords: RESEARCH; RESPIRATORY CARE; CLINICAL TRIALS; INSTITUTIONAL REVIEW BOARD; INFORMED CONSENT; RESEARCH METHODOLOGY

Document Type: Research article

Affiliations: 1: Department of Anesthesiology, University of Virginia Health System, Charlottesville, Virginia 2: Department of Anesthesiology, University of Virginia Health Science Center, PO Box 800710, Charlottesville VA 22908-0170;, Email: cgd8v@viriginia.edu

Publication date: 2004-10-01

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