Authors: Shrestha, Rabin K.¹; Stoller, James K.²; Honari, Golara³; Procop, Gary W.⁴; Gordon, Steven M.⁵

Source: Respiratory Care, Volume 49, Number 6, June 2004 , pp. 606-608(3)

Publisher: The Journal Respiratory Care Company

Abstract:

The use of humanized antibody against tumor necrosis factor alpha (TNF-α) may increase the risk of various opportunistic infections, including tuberculosis and fungal infections. We report a case of cryptococcal pneumonia in a patient who was taking infliximab for rheumatoid arthritis. A temporally related exposure history raised the possibility that our patient acquired the infection from his pet cockatiel. It seems prudent to advise patients receiving infliximab to avoid exposure to pet avian excreta.

Keywords: CRYPTOCOCCOSIS; CRYPTOCOCCUS; INFLIXIMAB; PNEUMONIA; TUMOR NECROSIS FACTOR; ZOONOSIS; IMMUNO-COMPROMISED HOST

Document Type: Case report

Affiliations: 1: Section of Clinical Microbiology, Department of Clinical Pathology, Cleveland, Ohio, L4, Division of Microbiology, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland OH 44195;, Email: shrestr@ccf.org 2: Division of Medicine and the Section of Respiratory Therapy, Department of Pulmonary, Allergy, and Critical Care Medicine, Cleveland, Ohio 3: Department of General Internal Medicine, Cleveland, Ohio 4: Section of Clinical Microbiology, Department of Clinical Pathology, Cleveland, Ohio 5: Department of Infectious Diseases—The Cleveland Clinic Foundation, Cleveland, Ohio

Publication date: 2004-06-01

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