Skip to main content

HPIEC determination of the content of acetate in hydroxyethyl starch 130/0.4 and electrolyte injection

Buy Article:

$20.00 + tax (Refund Policy)

Objective: To establish an high performance ion-exclusion chromatography method for determination of the content of sodium acetate in hydroxyethyl starch 130/0.4 and electrolyte injection. Methods: ICSep ICE-ORH-801 (6.5 mm×300 mm,5 μm ) column was adopted,with the mobile phase being 0.005 mol·L-1 sulfuric acid at the flow rate of 1.0 mL·min-1.The column temperature was set at 60 °C,and the detection wavelength 210 nm. Results: Good linearity was obtained for sodium acetate ranging from 2.0-16.0 μg ( r=0.9993),and the recovery of this method was 99.03% with RSD of 0.22%. Conclusion: The method is convenient,accurate,and can be used to determine the content of sodium acetate in hydroxyethyl starch 130/0.4 and electrolyte injection.

PLEASE NOTE: The full text of this publication is in Chinese.

Keywords: acetate; electrolyte; high performance ion-exclusion chromatography ( HPIEC ); hydroxyethyl starch; injection

Document Type: Research Article

Publication date: 01 January 2012

More about this publication?
  • Journal of Pharmaceutical Analysis is a professional journal administrated by China Association for Science and Technology, sponsored by Chinese Pharmaceutical Association, held by National Institutes for Food and Drug Control, edited and published by the Editorial Board of Journal of Pharmaceutical Analysis, and publicly distributed at home and abroad. It is one of the first group of journals that created by academic leaders in the field of drug control. It originated from Drug Control Communication which magazine was founded in 1951 and later been renamed in 1981. In 2005, it was changed from bi-monthly journal to monthly journal. Journal of Pharmaceutical Analysis is among core journals in nature sciences and even other Chinese core journals, whose main columns are research reports, communications, review, forum, information and etc. It mainly reports the latest research results, explore new theories, introduce new development, spread new techniques, and promote new methods of pharmaceutical analysis. Its contents include peer-reviewed research reports, research presentation and summary reviews on all aspects of pharmaceutical analysis including drug development, pharmaceutical manufacturing, clinical research, drug safety, quality assessment, and market surveillance. Main authors and target reader are professional and technical personnel engaged in research, application as well as higher education in pharmaceutical analysis.
  • Editorial Board
  • Information for Authors
  • Submit a Paper
  • Ingenta Connect is not responsible for the content or availability of external websites
  • Access Key
  • Free content
  • Partial Free content
  • New content
  • Open access content
  • Partial Open access content
  • Subscribed content
  • Partial Subscribed content
  • Free trial content