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Extraction of Notopterygium forbesii by surercritical CO2 extraction

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Objective:To optimize the extracting process for Notopterygium forbesii by supercritical CO2 extraction.Methods:The best conditions of the extracting essential oil from root of Notopterygium forbesii by SFE-CO2 were studied and chemical composition was determined by using the GC-MS.Results:The optimum process was as following:The temperature of extracting technique was 50 pressure 25 MPaextraction time 2 h and gas flow rate 65 kg·h-1;The extracting rate of essential oil was 88%,about 6 times to steam distillation.And 159 kinds of compound was identified from extracting essential oil,furthermore compound containing Cl,S,B,F,the Si element has not been reported in the related literature.Conclusion:Temperature and pressure are the key factors which affect extracting efficiency and stability of Notopterygium forbesii by supercritical CO2 extraction.

PLEASE NOTE: The full text of this publication is in Chinese.

Keywords: Notopterygium forbesii supercritical CO2 fluid extraction essential oil chemical composition

Document Type: Research Article

Publication date: 01 January 2009

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  • Journal of Pharmaceutical Analysis is a professional journal administrated by China Association for Science and Technology, sponsored by Chinese Pharmaceutical Association, held by National Institutes for Food and Drug Control, edited and published by the Editorial Board of Journal of Pharmaceutical Analysis, and publicly distributed at home and abroad. It is one of the first group of journals that created by academic leaders in the field of drug control. It originated from Drug Control Communication which magazine was founded in 1951 and later been renamed in 1981. In 2005, it was changed from bi-monthly journal to monthly journal. Journal of Pharmaceutical Analysis is among core journals in nature sciences and even other Chinese core journals, whose main columns are research reports, communications, review, forum, information and etc. It mainly reports the latest research results, explore new theories, introduce new development, spread new techniques, and promote new methods of pharmaceutical analysis. Its contents include peer-reviewed research reports, research presentation and summary reviews on all aspects of pharmaceutical analysis including drug development, pharmaceutical manufacturing, clinical research, drug safety, quality assessment, and market surveillance. Main authors and target reader are professional and technical personnel engaged in research, application as well as higher education in pharmaceutical analysis.
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