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SPECTROPHOTOMETRIC DETERMINATION OF DECANOYLACETALDEHYDE

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A new and sensitive spectrophotometric method for the determination of de-canoylacetaldehyde is describedThe method is based upon the formation of chelate compound from decanoylacetaldehyde and copper()in ammoniacal mediumExtract the chelate into chloroformadd the PAN[1-(2-pyridylazo)-2-naphthol]reagent and the P AN-Cu()complex is formedMeasure the absorbance of the solution at 570nm against a reagent blankwhere the apparent molar absorption coefficient is 5.42×104The absorption curve is linear in the range of 2-10μg/ml for decanoylacetaldehydeThe standard deviation is 1.07 and the recovery rate of the injection is 96.4Tween-80 and other monocarbonyl compounds do not interfereRatio of[Cu][Decanoylacetaldehyde]=1:2 is further proved by this method The stability constant(K=1×1012)is also determined

PLEASE NOTE: The full text of this publication is in Chinese.

Document Type: Research Article

Publication date: 01 May 1982

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  • Journal of Pharmaceutical Analysis is a professional journal administrated by China Association for Science and Technology, sponsored by Chinese Pharmaceutical Association, held by National Institutes for Food and Drug Control, edited and published by the Editorial Board of Journal of Pharmaceutical Analysis, and publicly distributed at home and abroad. It is one of the first group of journals that created by academic leaders in the field of drug control. It originated from Drug Control Communication which magazine was founded in 1951 and later been renamed in 1981. In 2005, it was changed from bi-monthly journal to monthly journal. Journal of Pharmaceutical Analysis is among core journals in nature sciences and even other Chinese core journals, whose main columns are research reports, communications, review, forum, information and etc. It mainly reports the latest research results, explore new theories, introduce new development, spread new techniques, and promote new methods of pharmaceutical analysis. Its contents include peer-reviewed research reports, research presentation and summary reviews on all aspects of pharmaceutical analysis including drug development, pharmaceutical manufacturing, clinical research, drug safety, quality assessment, and market surveillance. Main authors and target reader are professional and technical personnel engaged in research, application as well as higher education in pharmaceutical analysis.
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