Tuberculosis in recipients of solid-organ transplants during 1995–2015 in Cali, Colombia
OBJECTIVE: To determine treatment outcomes in SOT recipients with active TB.
DESIGN: A retrospective study of clinical and microbiological data and TB treatment outcomes.
RESULTS: Among the 2349 transplants assessed, active TB was detected in 31 recipients; 55% had pulmonary TB and 40% were sputum smear-positive. In 32% of the patients, TB was diagnosed 30 days after symptom onset, 77% of the patients were cured and 10% died. AGR occurred in 13%.
CONCLUSION: TB was diagnosed in <30 days. Anti-tuberculosis treatment without RMP (80% vs. 67%; P = 0.48, OR 0.5, 95%CI 0.07–3.55) and with moxifloxacin yielded higher treatment success rates and a lower risk of AGR.
Document Type: Research Article
Affiliations: 1: Department of Infectious Diseases, Fundacion Valle del Lili, Cali 2: Universidad Icesi, Cali 3: Clinical Research Center, Fundación Valle del Lili, Cali, Department of Public Health, Health Sciences Faculty, Universidad Icesi, Cali 4: Epidemiology Service, Public Health Agency of Barcelona and CIBER de Epidemiología y Salud Pública (CIBERESP), Barcelona 5: Hospital Clinic, Institut d'investigacions Biomèdiques August Pi i Sunyer, University of Barcelona, Barcelona, Spain
Publication date: 01 November 2017
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