Free Content Multidrug resistance in new tuberculosis patients: burden and implications [Short communication]

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In 2010, 30 countries with anti-tuberculosis drug resistance surveillance data were each estimated to have more than 700 multidrug-resistant tuberculosis (MDR-TB) cases among their notified TB cases. New TB patients comprised a median of 54% (interquartile range 45–67) of the MDR-TB cases. The occurrence of MDR-TB in a new TB patient is a warning sign that MDR-TB is spreading in a community. While MDR-TB case-finding efforts should first prioritize previously treated patients, reaching universal access requires rapidly adding other risk groups, and then all new TB patients. Epidemiological data as presented in this paper can help inform country scale-up plans.

Keywords: case finding; drug susceptibility testing; tuberculosis; universal access

Document Type: Research Article


Affiliations: 1: University of California, San Francisco, California, USA 2: Stop TB Department, World Health Organization, Geneva, Switzerland 3: Western Pacific Regional Office, World Health Organization, Manila, The Philippines 4: European Regional Office, World Health Organization, Copenhagen, Denmark 5: South East Asia Regional Office, World Health Organization, New Delhi, India 6: Program for Appropriate Technology in Health, Seattle, WA, USA

Publication date: April 1, 2013

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  • The International Journal of Tuberculosis and Lung Disease publishes articles on all aspects of lung health, including public health-related issues such as training programmes, cost-benefit analysis, legislation, epidemiology, intervention studies and health systems research. The IJTLD is dedicated to the continuing education of physicians and health personnel and the dissemination of information on tuberculosis and lung health world-wide.

    Certain IJTLD articles are selected for translation into French, Spanish, Chinese or Russian. They are available on the Union website

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