Chronic obstructive pulmonary disease and metabolic syndrome: a nationwide survey in Korea
OBJECTIVE: To evaluate the relationship between COPD and metabolic syndrome.
DESIGN: Among subjects aged ≥40 years from the 2001 Korean National Health and Nutrition Examination Survey, 1215 subjects with two or more acceptable spirometry measurements and complete anthropometric/laboratory examinations were analysed.
RESULTS: A total of 133 subjects (11%, 100 men and 33 women) were newly diagnosed with COPD (forced expiratory volume in 1 second/forced vital capacity ≤ 70%). The prevalence of metabolic syndrome, based on the National Cholesterol Education Program Adult Treatment Panel III, was significantly higher in COPD subjects compared with non-COPD subjects in both sexes (33.0% vs. 22.2% in men and 48.5% vs. 29.6% in women). In men, the risk of COPD was higher in subjects with metabolic syndrome than in those without (OR 2.03, 95%CI 1.08–3.80), after adjusting for potential confounders. There was a borderline significant association between COPD and abdominal obesity among the individual component of metabolic syndrome (OR 1.95, 95%CI 0.93–4.11).
CONCLUSION: In the Republic of Korea, metabolic syndrome was associated with COPD in men.
Document Type: Research Article
Affiliations: 1: Pulmonary and Critical Care Division, Department of Internal Medicine, Yonsei University College of Medicine, Seodaemun-gu, Seoul, Korea 2: Pulmonary and Critical Care Division, Department of Internal Medicine, and Institute of Chest Diseases, Yonsei University College of Medicine, Seodaemun-gu, Seoul, Korea 3: Department of Preventive Medicine, Yonsei University College of Medicine, Seodaemun-gu, Seoul, Korea
Publication date: 2012-05-01
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