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Free Content Investigation of space-time clusters and geospatial hot spots for the occurrence of tuberculosis in Beijing

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OBJECTIVE: To characterise the geographic and spatiotemporal distribution of confirmed tuberculosis (TB) cases in Beijing between 2005 and 2009.

DESIGN: The yearly notification rate maps were used to describe the distribution of confirmed adult TB patients. Spatial autocorrelation (Moran's I) and hot-spot analysis were adopted to detect the clusters and hot spots of TB.

RESULTS: The TB incidence rate (cases per 100 000 population) in Beijing increased from 29.8 in 2005 to 35.0 in 2009. The incidence rate was significantly higher in the Urban Development New District and the Ecologic Reservation Development District (>30/100 000) than in the other districts. There was a significant spatial autocorrelation throughout the city (u = 2.58, P = 0.01). Evident clusters were observed in the Capital Functional Core District and the Urban Function Extension District (Gi * > 1).

CONCLUSION: Spatial autocorrelation and hot-spot analysis may serve as efficient tools to detect space-time clusters and geospatial hot spots of TB incidence. Between 2005 and 2009, TB incidence in Beijing showed population density and mobility-dependent and eco-social status-dependent space-time clusters and geospatial hot spots.
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Keywords: geographic distribution; hot-spot analysis; spatial autocorrelation; tuberculosis

Document Type: Research Article

Affiliations: 1: Department of Epidemiology and Health Statistics, School of Public Health and Family Medicine, Capital Medical University, Beijing Key Laboratory of Epidemiology, Beijing, China; Center of Public Health Surveillance and Information Service, Chinese Center for Disease Control and Prevention, Beijing, China 2: Department of Epidemiology and Health Statistics, School of Public Health and Family Medicine, Capital Medical University, Beijing Key Laboratory of Epidemiology, Beijing, China 3: Department of Health Law, School of Health Administration and Education, Capital Medical University, Beijing, China

Publication date: 2012-04-01

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  • The International Journal of Tuberculosis and Lung Disease publishes articles on all aspects of lung health, including public health-related issues such as training programmes, cost-benefit analysis, legislation, epidemiology, intervention studies and health systems research. The IJTLD is dedicated to the continuing education of physicians and health personnel and the dissemination of information on tuberculosis and lung health world-wide.

    Certain IJTLD articles are selected for translation into French, Spanish, Chinese or Russian. They are available on the Union website

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