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Free Content Advancing the development of diagnostic tests and biomarkers for tuberculosis [Notes from the field]

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Abstract:

High costs and limited returns on investment have hampered progress in developing new diagnostic tests and treatments for tuberculosis (TB). We need new biomarkers to develop assays that can rapidly, efficiently and reliably detect Mycobacterium tuberculosis infection and disease, identify drug resistance and expedite drug and vaccine development. This can only be accomplished through cross-disciplinary collaborations to facilitate access to human specimens. The Food and Drug Administration, Centers for Disease Control and Prevention, National Institutes of Health, the industry and academia experts came together in a June 2010 workshop to examine the field of TB diagnostic test development and biomarker discovery, identify areas of most urgent need and formulate strategies to address those needs.

Keywords: TB; biomarkers; tuberculosis

Document Type: Short Communication

DOI: http://dx.doi.org/10.5588/ijtld.10.0712

Affiliations: 1: Office of Critical Path Programs, US Food and Drug Administration, Silver Spring, Maryland, USA 2: Mycobacteriology Laboratory Branch, Centers for Disease Control and Prevention, Atlanta, Georgia, USA 3: Tuberculosis and Other Mycobacterial Diseases Section, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA

Publication date: July 1, 2011

More about this publication?
  • The International Journal of Tuberculosis and Lung Disease publishes articles on all aspects of lung health, including public health-related issues such as training programmes, cost-benefit analysis, legislation, epidemiology, intervention studies and health systems research. The IJTLD is dedicated to the continuing education of physicians and health personnel and the dissemination of information on tuberculosis and lung health world-wide.

    Certain IJTLD articles are selected for translation into French, Spanish, Chinese or Russian. They are available on the Union website

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