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Free Content Mortality in successfully treated tuberculosis patients in southern Ethiopia: retrospective follow-up study

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Abstract:

SETTING: The tuberculosis (TB) programme in the Sidama zone of southern Ethiopia.

OBJECTIVE: To measure excess mortality in successfully treated TB patients.

DESIGN: In a retrospective cohort study of TB patients treated from 1998 to 2006, mortality was used as an outcome measure, and was calculated per 100 person-years of observation (PYO) from the date of completion of treatment to date of interview if the patient was alive, or to date of death. Kaplan-Meier and Cox regression methods were used to determine the survival and hazard ratios. An indirect method of standardisation was used to calculate the standard mortality ratio (SMR).

RESULTS: A total of 725 TB patients were followed for 2602 person-years: 91.1% (659/723) were alive and 8.9% (64/723) had died. The mortality rate was 2.5% per annum. Sex, age and occupation were associated with high mortality. More deaths occurred in non-farmers (SMR = 9.95, 95%CI 7.17–12.73).

DISCUSSION: The mortality rate was higher in TB patients than in the general population. More deaths occurred in non-farmers, men and the elderly. Further studies are required to identify the causes of death in these patients.

Keywords: Ethiopia; mortality; standard mortality ratio; tuberculosis

Document Type: Regular Paper

Affiliations: 1: Centre for International Health, University of Bergen, Overlege Danielsens Hus, Bergen, Norway; Southern Nations, Nationalities and Peoples' Regional Health Bureau, Hawassa, Ethiopia 2: Centre for International Health, University of Bergen, Overlege Danielsens Hus, Bergen, Norway

Publication date: July 1, 2010

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  • The International Journal of Tuberculosis and Lung Disease publishes articles on all aspects of lung health, including public health-related issues such as training programmes, cost-benefit analysis, legislation, epidemiology, intervention studies and health systems research. The IJTLD is dedicated to the continuing education of physicians and health personnel and the dissemination of information on tuberculosis and lung health world-wide.

    Certain IJTLD articles are selected for translation into French, Spanish, Chinese or Russian. They are available on the Union website

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