Mortality in successfully treated tuberculosis patients in southern Ethiopia: retrospective follow-up study
Abstract:SETTING: The tuberculosis (TB) programme in the Sidama zone of southern Ethiopia.
OBJECTIVE: To measure excess mortality in successfully treated TB patients.
DESIGN: In a retrospective cohort study of TB patients treated from 1998 to 2006, mortality was used as an outcome measure, and was calculated per 100 person-years of observation (PYO) from the date of completion of treatment to date of interview if the patient was alive, or to date of death. Kaplan-Meier and Cox regression methods were used to determine the survival and hazard ratios. An indirect method of standardisation was used to calculate the standard mortality ratio (SMR).
RESULTS: A total of 725 TB patients were followed for 2602 person-years: 91.1% (659/723) were alive and 8.9% (64/723) had died. The mortality rate was 2.5% per annum. Sex, age and occupation were associated with high mortality. More deaths occurred in non-farmers (SMR = 9.95, 95%CI 7.17–12.73).
DISCUSSION: The mortality rate was higher in TB patients than in the general population. More deaths occurred in non-farmers, men and the elderly. Further studies are required to identify the causes of death in these patients.
Document Type: Regular Paper
Affiliations: 1: Centre for International Health, University of Bergen, Overlege Danielsens Hus, Bergen, Norway; Southern Nations, Nationalities and Peoples' Regional Health Bureau, Hawassa, Ethiopia 2: Centre for International Health, University of Bergen, Overlege Danielsens Hus, Bergen, Norway
Publication date: July 1, 2010
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