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Free Content Rapid diagnosis of tuberculosis and multidrug resistance with the microscopic observation drug susceptibility assay in Ecuador [Notes from the field]

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A collaborative project was established between the Alli Causai Foundation in Ambato, Ecuador, and the University of Genoa, Italy, to introduce the microscopic observation drug susceptibility (MODS) assay for the rapid identification of Mycobacterium tuberculosis in Ecuador. A total of 507 samples were evaluated during a 10-month period, and DNA was extracted from each isolate and sent to Genoa for confirmatory molecular analysis. M. tuberculosis was identified in 45 samples by MODS, and drug resistance was observed in approximately 21% of the isolates, with four multidrug-resistant strains detected in two patients.

Keywords: Ecuador; MODS; tuberculosis

Document Type: Short Communication

Affiliations: 1: Hospital Alli Causai, Ambato, Ecuador 2: Division of Microbiology ‘CA Romanzi’, Dipartimento Interdisciplinare di Scienze Specialistiche Chirurgiche, di Microbiologia e Dei Trapianti d'Organo (DISCMIT), University of Genoa, Genoa, Italy 3: Advanced Biotechnology Center, Genoa, Italy

Publication date: June 1, 2010

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  • The International Journal of Tuberculosis and Lung Disease publishes articles on all aspects of lung health, including public health-related issues such as training programmes, cost-benefit analysis, legislation, epidemiology, intervention studies and health systems research. The IJTLD is dedicated to the continuing education of physicians and health personnel and the dissemination of information on tuberculosis and lung health world-wide.

    Certain IJTLD articles are selected for translation into French, Spanish, Chinese or Russian. They are available on the Union website

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