Rapid diagnosis of tuberculosis and multidrug resistance with the microscopic observation drug susceptibility assay in Ecuador [Notes from the field]
Abstract:A collaborative project was established between the Alli Causai Foundation in Ambato, Ecuador, and the University of Genoa, Italy, to introduce the microscopic observation drug susceptibility (MODS) assay for the rapid identification of Mycobacterium tuberculosis in Ecuador. A total of 507 samples were evaluated during a 10-month period, and DNA was extracted from each isolate and sent to Genoa for confirmatory molecular analysis. M. tuberculosis was identified in 45 samples by MODS, and drug resistance was observed in approximately 21% of the isolates, with four multidrug-resistant strains detected in two patients.
Document Type: Short Communication
Affiliations: 1: Hospital Alli Causai, Ambato, Ecuador 2: Division of Microbiology ‘CA Romanzi’, Dipartimento Interdisciplinare di Scienze Specialistiche Chirurgiche, di Microbiologia e Dei Trapianti d'Organo (DISCMIT), University of Genoa, Genoa, Italy 3: Advanced Biotechnology Center, Genoa, Italy
Publication date: June 1, 2010
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