Authors: Cojocaru, C.¹; van Hest, N.A.²; Mihaescu, T.¹; Davies, P.D.³

Source: The International Journal of Tuberculosis and Lung Disease, Volume 13, Number 9, September 2009 , pp. 1094-1099(6)

Publisher: International Union Against Tuberculosis and Lung Disease

Abstract:

SETTING: Iasi County, Romania.

OBJECTIVE: To assess the completeness of notification of adult tuberculosis (TB; age ≥15 years) in 2004.

DESIGN: Record-linkage and capture-recapture analysis of three TB-related registers: a notification register, a laboratory register and a prescriptions register.

RESULTS: After record linkage, the observed completeness of the notification register was 86.4%, giving an observed adult TB incidence rate of 202 per 100 000 population. After capture-recapture analysis, internal validity analysis and application of alternative truncated population estimation models, the estimated completeness of the notification register was 82-85%, giving an estimated adult TB incidence rate of between 204 and 212/100 000.

CONCLUSION: This study shows that the severity of the TB problem in Iasi County is under-reported. The results are in agreement with a previous estimate of the undernotification of TB in Romania by the the World Health Organization.

Keywords: tuberculosis; epidemiology; undernotification; capture-recapture analysis; Romania

Document Type: Regular paper

Affiliations: 1: Pulmonary Disease Division, University of Medicine and Pharmacy `Gr T Popa', Iasi, Romania 2: Department of Tuberculosis Control, Municipal Public Health Service Rotterdam-Rijnmond, Rotterdam, The Netherlands 3: The Cardiothoracic Centre Liverpool National Health Service Trust, Liverpool, UK

Publication date: 2009-09-01

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