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Free Content The diagnosis and misdiagnosis of tuberculosis [State of the art series. Tuberculosis. Edited by I. D. Rusen. Number 1 in the series]

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There are two worlds when it comes to the diagnosis of tuberculosis (TB). One world has only smear microscopy at its disposal. There may also be some radiological facilities, usually at the patients' expense. The other world has all modern techniques available, including culture, nucleic acid amplification, molecular diagnostics and sophisticated radiological techniques such as computed tomography and positron emission tomography scanning. The ability to diagnose or misdiagnose TB will vary across these two worlds. In this review, we provide an overview of clinical, radiological, molecular and immunological diagnosis of TB and highlight the common difficulties and pitfalls in TB diagnosis.
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Document Type: Invited Paper

Affiliations: 1: Tuberculosis Research Unit, Cardiothoracic Centre, Liverpool, UK 2: Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Montreal, Quebec, Canada

Publication date: 2008-11-01

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  • The International Journal of Tuberculosis and Lung Disease publishes articles on all aspects of lung health, including public health-related issues such as training programmes, cost-benefit analysis, legislation, epidemiology, intervention studies and health systems research. The IJTLD is dedicated to the continuing education of physicians and health personnel and the dissemination of information on tuberculosis and lung health world-wide.

    Certain IJTLD articles are selected for translation into French, Spanish, Chinese or Russian. They are available on the Union website

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