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Free Content Outcomes in HIV-infected patients who develop tuberculosis after starting antiretroviral treatment in Malawi [Short Communication]

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Abstract:

A retrospective review was conducted of patients starting antiretroviral treatment (ART) at Mzuzu Central Hospital, Malawi, to identify those who developed tuberculosis (TB) within 6 months of commencing ART and document their treatment outcomes. Of 2933 patients, 22 (0.75%) developed active TB, 17 (77%) of whom had commenced ART as a result of unexplained weight loss and/or fever. Of those who developed TB, 41% successfully completed anti-tuberculosis treatment, with lower survival probabilities than patients who did not develop TB. Easier methods are needed to diagnose TB in human immunodeficiency virus-infected patients and to prevent patients from developing TB while on ART.

Keywords: HIV/AIDS; Malawi; antiretroviral treatment; treatment outcomes; tuberculosis

Document Type: Short Communication

Affiliations: 1: International Medical Cooperation and Development Center, Pingtung Christian Hospital, Ping Tung, Taiwan; and College of Public Health, National Taiwan University, Taipei City, Taiwan 2: Mzuzu Central Hospital, Ministry of Health, Mzuzu, Malawi 3: Ping Tung Hospital, Department of Health, Ping Tung, Taiwan; and Bureau of International Cooperation, Department of Health, Taipei, Taiwan 4: Clinical HIV Unit, Ministry of Health, Lilongwe, Malawi 5: Clinical HIV Unit, Ministry of Health, Lilongwe, Malawi; and Management Sciences for Health, Lilongwe, Malawi 6: Clinical HIV Unit, Ministry of Health, Lilongwe, Malawi; Family Health International, Malawi Country Office, Lilongwe, Malawi; and London School of Hygiene and Tropical Medicine, London, UK

Publication date: June 1, 2008

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  • The International Journal of Tuberculosis and Lung Disease publishes articles on all aspects of lung health, including public health-related issues such as training programmes, cost-benefit analysis, legislation, epidemiology, intervention studies and health systems research. The IJTLD is dedicated to the continuing education of physicians and health personnel and the dissemination of information on tuberculosis and lung health world-wide.

    Certain IJTLD articles are selected for translation into French, Spanish, Chinese or Russian. They are available on the Union website

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