Annual risk of tuberculosis infection in West Sumatra Province, Indonesia
Abstract:OBJECTIVE: To estimate the annual risk of tuberculosis infection (ARTI) among children attending elementary school Classes I–III in West Sumatra Province, Indonesia.
METHODS: The survey was designed to estimate ARTI among children, irrespective of BCG scar status. Fieldwork was carried out in 72 schools selected by two-stage sampling. Children were administered 2 TU of purified protein derivative RT23 with Tween 80 intradermally on the mid-anterior aspect of the left forearm. The maximum transverse diameter of induration was measured at about 72 h. Analysis was carried out among 5653 satisfactorily test-read children aged 6–9 years.
RESULTS: The estimation by mirror-image method among all children (without and with BCG scar) revealed an ARTI of between 1% and 1.3%. The estimated ARTIs among children without and with BCG scar varied between 0.8–1.3% and 0.9–1.4%, respectively, using the mirror-image method, anti-mode method and mixture model.
CONCLUSION: Tuberculosis control efforts need to be intensified to reduce the risk of transmission of infection.
Document Type: Regular Paper
Affiliations: 1: Centre for Health Research, University of Indonesia, Jakarta, Indonesia 2: National TB Programme, Directorate General of Communicable Disease Control and Environmental Health, Jakarta, Indonesia 3: World Health Organization, Jakarta, Indonesia 4: World Health Organization, Jakarta, Indonesia; and National Tuberculosis Institute, Bangalore, India 5: World Health Organization, Jakarta, Indonesia; and European Centre for Disease Prevention and Control, Stockholm, Sweden 6: National Tuberculosis Institute, Bangalore, India
Publication date: 2008-03-01
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