Tuberculosis in European cities: establishment of a patient monitoring system over 10 years in Paris, France
METHODS: All patients placed under treatment in four hospitals and five out-patient Social Medical Centres in Paris were followed up between 1996 and 2005. Patient monitoring and evaluation were performed using a new software programme, TB-INFO.
RESULTS: In a cohort of 1127 patients, 76% had pulmonary TB, of whom 39% were smear-positive, 81% were foreign-born and 9.3% were human immunodeficiency virus positive. At the end of the follow-up, 16% were cured and 54% had completed treatment. Among the 1118 non-multidrug-resistant patients, these percentages were 17% and 46%, respectively, for smear-positive pulmonary patients. Some patients died (1.9%) or failed treatment (0.1%), but many more defaulted (20.5%) as they interrupted treatment (1.5%), were lost to follow-up (19.5%) or were transferred out (7.9%).
CONCLUSIONS: This 10-year follow-up of TB patients, managed with TB-INFO software, shows that a patient monitoring system can be implemented in France, providing essential information. Treatment success in this cohort of patients was far below the WHO target.
Document Type: Regular Paper
Affiliations: 1: Service de Médecine Interne et Pathologie Vasculaire, Hôpital Saint-Louis, Paris, France 2: Département de Biostatistique et Informatique Médicale, Hôpital Saint-Louis, Paris, France 3: Cellule Tuberculose, Direction de l'Action Sociale de l'Enfance et de la Santé, Paris, France 4: Service de Médecine Interne, Hôpital Jean Verdier, Bondy, France 5: Centre Hospitalier de Carnelle, Saint Martin du Tertre, France 6: Service de Pneumologie, Hôpital Saint-Louis, Paris, France 7: Service de Maladies Infectieuses, Hôpital Saint-Louis, Paris, France 8: Institut National de Veille Sanitaire, Saint-Maurice, France 9: European Centre for Disease Prevention and Control, Stockholm, Sweden 10: World Health Organization Regional Office for Europe, Copenhagen, Denmark 11: Service de Microbiologie, Hôpital Raymond Poincaré, Garches, France 12: Stop TB Department, World Health Organization, Geneva, Switzerland 13: URL: http://www.tb-info.org
Publication date: 2007-09-01
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