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Free Content Clinical and epidemiological evaluation of tuberculosis in Serbia, 1990–2004

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SETTING: Republic of Serbia, excluding Kosovo.

OBJECTIVE: To estimate the clinical and epidemiological pattern of tuberculosis (TB) in Serbia during the period 1990–2004.

DESIGN: A retrospective analysis of clinical and epidemiological data on TB patients registered in annual TB reports.

RESULTS: During the 15-year period, TB incidence levelled off in Serbia. The slightly decreasing trend occurred in both total pulmonary TB (PTB) and laboratory confirmed PTB (PTB+) incidence (P > 0.05), while the trend of extra-pulmonary TB (EPTB) incidence increased slightly (P > 0.05). During the same period, TB mortality showed a significantly decreasing trend (P < 0.05). The mean annual proportion of PTB+ cases among newly reported PTB cases was 62.7%. The mean proportion of EPTB cases among total TB cases was 6.1%. The mean percentage of cases with resistance to at least one anti-tuberculosis drug was 4.8%.

CONCLUSION: Thanks to the good organisation and efficient work of anti-tuberculosis dispensaries in Serbia, as well as to the low incidence of AIDS and low frequency of Mycobacterium tuberculosis resistant strains, TB incidence did not increase during the period observed and TB mortality significantly decreased, despite markedly deteriorated socio-economic conditions during the 1990s.

Keywords: Serbia; incidence; mortality; tuberculosis

Document Type: Regular Paper

Affiliations: 1: Institute of Pulmonary Diseases and Tuberculosis, Clinical Center of Serbia, Belgrade, Serbia 2: Institute of Epidemiology, School of Medicine, Belgrade, Serbia 3: Institute of Radiology, Clinical Center of Serbia, Belgrade, Serbia

Publication date: June 1, 2007

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  • The International Journal of Tuberculosis and Lung Disease publishes articles on all aspects of lung health, including public health-related issues such as training programmes, cost-benefit analysis, legislation, epidemiology, intervention studies and health systems research. The IJTLD is dedicated to the continuing education of physicians and health personnel and the dissemination of information on tuberculosis and lung health world-wide.

    Certain IJTLD articles are selected for translation into French, Spanish, Chinese or Russian. They are available on the Union website

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