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Free Content Role of the C-reactive protein for the diagnosis of TB among military personnel in South Korea [Short Communication]

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Clinicians are frequently faced with the task of differentiating between pulmonary tuberculosis (PTB) and pneumonia. We evaluated the role of the C-reactive protein test (CRP) for differentiating between TB and pneumonia among military personnel in South Korea. Only immunocompetent males were eligible. Forty-six patients with PTB and 67 with pneumonia were enrolled prospectively. Median CRP concentration was lower in patients with TB than in patients with non-tuberculous pneumonia (3.2 mg/dl [range 0.1–15.7 mg/dl] vs. 8.3 mg/dl [range 0.2–33.7 mg/dl], P < 0.001). The sensitivity and specificity for TB of a low CRP concentration (<11.2 mg/dl) in serum was 93.3% and 40.9%, respectively. CRP concentration measurement might be useful for eliminating the diagnosis of TB.

Keywords: C-reactive protein; community-acquired pneumonia; tuberculin skin test; tuberculosis

Document Type: Short Communication

Affiliations: 1: Department of Internal Medicine, Armed Forces Capital Hospital, Seoul, Republic of Korea 2: Department of Radiology, Armed Forces Capital Hospital, Seoul, Republic of Korea 3: Korea Center for Disease Control & Prevention, Seoul, Republic of Korea 4: Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine and Lung Institute, Seoul National University College of Medicine, Seoul, Republic of Korea

Publication date: February 1, 2007

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  • The International Journal of Tuberculosis and Lung Disease publishes articles on all aspects of lung health, including public health-related issues such as training programmes, cost-benefit analysis, legislation, epidemiology, intervention studies and health systems research. The IJTLD is dedicated to the continuing education of physicians and health personnel and the dissemination of information on tuberculosis and lung health world-wide.

    Certain IJTLD articles are selected for translation into French, Spanish, Chinese or Russian. They are available on the Union website

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