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Free Content Application of the Genotype® MTBDR assay directly on sputum specimens [Technical Note]

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Abstract:

The Genotype® MTBDR assay was tested for its capability to detect rifampicin (RMP) and isoniazid (INH) resistance (r) and susceptibility (s) directly from 42 smear-positive sputum specimens (15 RMPr/INHr, 2 RMPs/INHr and 25 RMPs/INHs Mycobacterium tuberculosis complex strains). The concordance between the MTBDR assay and conventional drug susceptibility testing was 100%.

Keywords: Genotype® MTBDR; sputum samples; tuberculosis

Document Type: Short Communication

Affiliations: Forschungszentrum Borstel, Nationales Referenzzentrum für Mykobakterien, Borstel, Germany

Publication date: September 1, 2006

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  • The International Journal of Tuberculosis and Lung Disease publishes articles on all aspects of lung health, including public health-related issues such as training programmes, cost-benefit analysis, legislation, epidemiology, intervention studies and health systems research. The IJTLD is dedicated to the continuing education of physicians and health personnel and the dissemination of information on tuberculosis and lung health world-wide.

    Certain IJTLD articles are selected for translation into French, Spanish, Chinese or Russian. They are available on the Union website

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