Authors: Koksalan, O.K.¹; Kilicaslan, Z.²; Zanlier, G.¹; Guzel, R.¹; Seber, E.³

Source: The International Journal of Tuberculosis and Lung Disease, Volume 10, Number 4, April 2006 , pp. 469-472(4)

Publisher: International Union Against Tuberculosis and Lung Disease

Abstract:

To determine the prevalence of Beijing genotype Mycobacterium tuberculosis in Istanbul, 4069 strains were subjected to DNA fingerprinting. This is the first study to reveal the presence of the Beijing genotype in Istanbul. The prevalence rate was estimated as 1.13%, and it was shown that these strains were carried over from countries of the former Soviet Union. The study also showed that the prevalence of the Beijing genotype among at least rifampicin (RMP) resistant strains was significantly higher (2.7%) than among RMP-susceptible strains (0.9%).

Keywords: tuberculosis; molecular epidemiology; DNA fingerprinting; Beijing genotype

Document Type: Short communication

Affiliations: 1: Molecular Tuberculosis Epidemiology Laboratory, Institute for Medical Experimental Research (DETAE), Istanbul University, Istanbul, Turkey 2: Department of Chest Diseases, Istanbul Medical Faculty, Istanbul University, Istanbul, Turkey 3: Central Microbiology Laboratory, Istanbul Union Against Tuberculosis, Istanbul, Turkey

Publication date: 2006-04-01

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• The International Journal of Tuberculosis and Lung Disease publishes articles on all aspects of lung health, including public health-related issues such as training programmes, cost-benefit analysis, legislation, epidemiology, intervention studies and health systems research. The IJTLD is dedicated to the continuing education of physicians and health personnel and the dissemination of information on tuberculosis and lung health world-wide.

  Certain IJTLD articles are selected for translation into French, Spanish, Chinese or Russian. They are available on the Union website

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