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Free Content IS6110 restriction fragment length polymorphism of Mycobacterium tuberculosis isolates from an area of Casablanca, Morocco [Short Communication]

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Abstract:

Using IS6110 RFLP, 61 isolates recovered from new cases of pulmonary tuberculosis (TB) were compared from September to December 1999 in Casablanca, Morocco, a city with a high incidence of TB. The majority of the isolates (92%) harboured 6–14 copies of IS6110. The minimal fraction of patients in groups of recently acquired infection is 13.1%. This preliminary study showed that IS6110 RFLP is a suitable method for fingerprinting Mycobacterium tuberculosis in Casablanca. The unexpectedly low level of recent transmission of TB found in this study deserves further studies involving higher numbers of isolates recovered during a longer recruitment period.

Keywords: Morocco; RFLP; tuberculosis

Document Type: Short Communication

Affiliations: 1: Microbiology Laboratory, Ibn Rochd University Hospital, Casablanca, Morocco 2: Microbiology Laboratory, Ibn Rochd University Hospital, Casablanca, Morocco; and Microbiology Laboratory, Faculté de Médecine, Casablanca, Morocco 3: Centre de Diagnostic Spécialisé de la Tuberculose Casablanca-Anfa, Casablanca, Morocco 4: Biology Department, Faculté des Sciences BenMsick, Casablanca, Morocco 5: Institut Pasteur, Centre National de Référence des Mycobactéries, Paris, France

Publication date: November 1, 2005

More about this publication?
  • The International Journal of Tuberculosis and Lung Disease publishes articles on all aspects of lung health, including public health-related issues such as training programmes, cost-benefit analysis, legislation, epidemiology, intervention studies and health systems research. The IJTLD is dedicated to the continuing education of physicians and health personnel and the dissemination of information on tuberculosis and lung health world-wide.

    Certain IJTLD articles are selected for translation into French, Spanish, Chinese or Russian. They are available on the Union website

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