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Free Content Structured behavioral intervention to increase children's adherence to treatment for latent tuberculosis infection

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SETTING: San Diego, California public health department tuberculosis clinic.

OBJECTIVE: To evaluate the effectiveness of a behavioral intervention (the Treasure Chest) that employed the behavior modification techniques of self-monitoring and positive reinforcement to increase adherence to therapy for latent tuberculosis infection (LTBI) in children.

DESIGN: A retrospective study utilizing a historical comparison group. The treatment adherence of children who attended San Diego County TB Control Program (SDCTBCP) clinics with positive tuberculin skin tests who were started on LTBI treatment prior to Treasure Chest program implementation (n = 841) was compared to that of SDCTBCP children enrolled in the Treasure Chest program (n = 741).

RESULTS: Logistic regression analysis demonstrated that children who participated in the Treasure Chest program were 2.4 times more likely to complete therapy than those who did not receive the intervention.

CONCLUSION: The Treasure Chest intervention is effective in increasing adherence to LTBI therapy in children.

Keywords: adherence; incentives; latent tuberculosis infection; tuberculosis

Document Type: Regular Paper

Affiliations: 1: Graduate School of Public Health, San Diego State University, San Diego, California, USA 2: Tuberculosis Control Program, San Diego County Health and Human Services Agency, San Diego, California, USA

Publication date: 2005-04-01

More about this publication?
  • The International Journal of Tuberculosis and Lung Disease publishes articles on all aspects of lung health, including public health-related issues such as training programmes, cost-benefit analysis, legislation, epidemiology, intervention studies and health systems research. The IJTLD is dedicated to the continuing education of physicians and health personnel and the dissemination of information on tuberculosis and lung health world-wide.

    Certain IJTLD articles are selected for translation into French, Spanish, Chinese or Russian. They are available on the Union website

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