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Free Content Polymerase chain reaction based detection of Mycobacterium tuberculosis complex in lupus vulgaris: a case report [Case Study]

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Lupus vulgaris (LV), the commonest of all forms of cutaneous tuberculosis, can affect the earlobes. Authors present a 20-year-old male patient with LV of the left earlobe initially misdiagnosed as pyoderma and treated superfluously with antibiotics at different intervals over the last 4 years in another hospital. Mycobacteria could not be seen or isolated by stained smears or conventional or radiometric culture methods from the skin biopsy specimens. Suspected clinical diagnosis of our patient was LV. This was supported by positive polymerase chain reaction assay and histological findings. The lesion was treated successfully with anti-tuberculosis chemotherapy, further confirming the diagnosis of LV.

Keywords: Mycobacterium tuberculosis complex; cutaneous tuberculosis; lupus vulgaris; polymerase chain reaction

Document Type: Short Communication

Affiliations: 1: Department of Microbiology and Clinical Microbiology, Gulhane Military Medical Academy, Ankara, Turkey 2: Department of Dermatology, Gulhane Military Medical Academy, Ankara, Turkey 3: Department of Pathology, Gulhane Military Medical Academy, Ankara, Turkey

Publication date: September 1, 2004

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  • The International Journal of Tuberculosis and Lung Disease publishes articles on all aspects of lung health, including public health-related issues such as training programmes, cost-benefit analysis, legislation, epidemiology, intervention studies and health systems research. The IJTLD is dedicated to the continuing education of physicians and health personnel and the dissemination of information on tuberculosis and lung health world-wide.

    Certain IJTLD articles are selected for translation into French, Spanish, Chinese or Russian. They are available on the Union website

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