Risk of infection with Mycobacterium tuberculosis in Malawi: national tuberculin survey 1994
Abstract:OBJECTIVE: To estimate the annual risk of tuberculosis infection among schoolchildren in Malawi.
METHODS: A school survey was conducted in twelve randomly selected districts in Malawi. Children in standard 1–4 and aged 6–11 years were eligible. Tuberculin skin testing was performed according to World Health Organization/International Union Against Tuberculosis and Lung Disease guidelines.
RESULTS: Of the 17123 eligible children, 80% were tested. Of those tested 79% were read. The prevalence of infection according to various criteria was 9–12% in children without bacille Calmette-Guérin (BCG) scar. The prevalence of reactions of 10 mm or more was lower in girls than in boys, increased with age, and was higher in those with than in those without BCG scar. The annual risk of infection was estimated to be within the range 0.6–1.4%.
CONCLUSION: Annual risk of infection in Malawi was in the order of 1%. This study is expected to provide valuable baseline information for an assessment of the impact of human immunodeficiency virus (HIV) on tuberculosis transmission in Malawi.
Document Type: Regular Paper
Affiliations: 1: Community Health Sciences Unit, Tuberculosis Control Programme, Lilongwe, Malawi 2: Royal Netherlands Tuberculosis Association (KNCV) and International Tuberculosis Surveillance Centre (ITSC), The Hague, The Netherlands; and International Union Against Tuberculosis and Lung Disease, Paris, France 3: Royal Netherlands Tuberculosis Association (KNCV) and International Tuberculosis Surveillance Centre (ITSC), The Hague, The Netherlands
Publication date: June 1, 2004
The International Journal of Tuberculosis and Lung Disease publishes articles on all aspects of lung health, including public health-related issues such as training programmes, cost-benefit analysis, legislation, epidemiology, intervention studies and health systems research. The IJTLD is dedicated to the continuing education of physicians and health personnel and the dissemination of information on tuberculosis and lung health world-wide.
Certain IJTLD articles are selected for translation into French, Spanish, Chinese or Russian. They are available on the Union website
- Editorial Board
- Information for Authors
- Subscribe to this Title
- International Journal of Tuberculosis and Lung Disease
- Public Health Action
- Ingenta Connect is not responsible for the content or availability of external websites