Authors: Sina B.J.¹; Molyneux E.²

Source: The International Journal of Tuberculosis and Lung Disease, Volume 8, Number 5, May 2004 , pp. 683-686(4)

Publisher: International Union Against Tuberculosis and Lung Disease

Abstract:

In 2002, an international Workshop on Tuberculosis in Children was held to determine priority areas for basic, clinical and programmatic research to improve paediatric TB practice. During the workshop, issues related to the ethical treatment of children as research subjects, particularly in resource-poor settings, were identified as major constraints to the goal of expanding paediatric TB research. Based on participation in the workshop discussions, this article proposes concrete activities that can begin to address the ethical barriers. The time and costs associated with creating collaborative scientific and ethical research projects between high and low-income countries should be supported in grants for paediatric TB research studies in developing countries. Paediatric TB researchers in developing countries should be given opportunities to participate in international programmes that develop bioethics expertise. Relevant case studies of paediatric research in developing countries can assist ethical review committees in industrialised countries in understanding the special issues related to paediatric research in resource-limited settings. Paediatricians in developing countries need to be included in childhood TB research studies and ethical review committees.

Keywords: bioethics; developing countries; paediatric research

Document Type: Invited paper

Affiliations: 1: Division of Training and Research, Fogarty International Center, National Institutes of Health, Bethesda, Maryland, USA 2: Department of Paediatrics, Malawi College of Medicine, Blantyre, Malawi

Publication date: 2004-05-01

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• The International Journal of Tuberculosis and Lung Disease publishes articles on all aspects of lung health, including public health-related issues such as training programmes, cost-benefit analysis, legislation, epidemiology, intervention studies and health systems research. The IJTLD is dedicated to the continuing education of physicians and health personnel and the dissemination of information on tuberculosis and lung health world-wide.

  Certain IJTLD articles are selected for translation into French, Spanish, Chinese or Russian. They are available on the Union website

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