Free Content Cost-effectiveness analysis of the Russian treatment scheme for tuberculosis versus short-course chemotherapy: results from Tomsk, Siberia

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SETTING: Tomsk Oblast, Siberia.

OBJECTIVE: To assess the cost-effectiveness of individualised Russian treatment and short-course chemotherapy (SCC) regimens for new WHO Category I tuberculosis patients.

DESIGN: Analysis of costs incurred by the provider, the household and society as a whole for both treatment approaches, and a sensitivity analysis for SCC with hospitalisation for 2 weeks (patients theoretically at low risk of defaulting) and 2 months (patients theoretically at risk of defaulting). Outcomes were measured as cost per case cured and year of life saved, with cure rates based on a locally conducted trial.

RESULTS: The cost per cure using the individualised Russian treatment was US$2295, vs. US$1901 when using SCC. The costs per year of life saved were respectively US$123 and US$103. The cost per cure was US$1457 for SCC with 2 months hospitalisation and US$556 for SCC with 2 weeks hospitalisation, with costs per year of life saved of US$79 and US$30, respectively.

CONCLUSION: Major financial savings for both the provider and the household, with cure rates similar to those obtained with the Russian treatment scheme, can be achieved in Tomsk when embarking on SCC with 2 weeks and 2 months hospitalisation.

Keywords: Russian treatment; cost-effectiveness analysis; short-course chemotherapy; tuberculosis

Document Type: Regular Paper

Affiliations: 1: Merlin (Medical Emergency Relief International), Borough, London, UK 2: Tomsk Oblast TB Dispensary, Tomsk, Siberia, Russian Federation

Publication date: May 1, 2002

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  • The International Journal of Tuberculosis and Lung Disease publishes articles on all aspects of lung health, including public health-related issues such as training programmes, cost-benefit analysis, legislation, epidemiology, intervention studies and health systems research. The IJTLD is dedicated to the continuing education of physicians and health personnel and the dissemination of information on tuberculosis and lung health world-wide.

    Certain IJTLD articles are selected for translation into French, Spanish, Chinese or Russian. They are available on the Union website

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